![]() ![]() Since sodium hydroxide is a bacteriostat, it is also useful for storage. sodium chloride, to the sodium hydroxide solution to combine cleaning with sanitization as well. It is common practice in industrial manufacturing to save time by adding salt, e.g. Sodium hydroxide is also effective for inactivating most viruses, bacteria, yeasts and endotoxins. ![]() If lipids are bound to a protein, an increased concentration of sodium hydroxide may be required for effective cleaning. Its use with affinity media is restricted due to the limited stability of affinity ligands. Sodium hydroxide is widely accepted for cleaning empty equipment, cleaning packed chromatography columns (cleaning-in-place, CIP), sanitizing and storing chromatography media and systems.įor CIP, sodium hydroxide has been extensively used to remove proteins and nucleic acids from ion exchange, hydrophobic interaction and gel filtration media. ![]()
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